GLP-1 News

Does anyone get those splits in the corners of your lips every now and then?? They hurt so bad!!

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Here we go, 1st shot down

I took my first 2.5mg shot this evening at 8pm PST, and did my "before" pictures, as well as "before" measurements. I've had the medicine for quite some time, but just wasn't able…

Switching

I've been on ozempic for 1 year - 2mg SW 231 CW 195 Been at a stall for atleast 6 months Use walking pad and do kettlebell workouts My question is has anyone switched to…

Can I purchase separate needles?

Hi, Migrating to Ozempic from Rybelsus. Will be finishing my final dose in about a week and then will make the switch. I already have my Ozempic pen and have been checking out…

Ozempic or die

Can I get ozempic or moonjaroo with tricare? If is yes say how if it's not say WHY???!! submitted by /u/Crazy_Spoiled69 [link] [comments]

Progress 🙌🏻

In the first picture, the dress fit but was hard to zip up, and I couldn't wear my bra with it. Now I can wear my bra with it and I don't even have to unzip it to get it on! *Pics…

It has been one hella of a year

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It has been one hella of a year

I want to start by saying that I weighed 105 kilos, I was an alcoholic (in June it’s gonna be my 2 year sober) I’ve been always struggling with mental health and I don’t wanna…

1 year….51 pounds

submitted by /u/EqualEffort148 [link] [comments]

Ozempic and smoking

Has smoking made you feel worse while taking ozempic? Have the side effects gotten worse? submitted by /u/Electrical_Flower338 [link] [comments]

Wide Calf Boots

Went to dinner last night and I had to dress up for the restaurant. Pulled out my trusty wide calf boots and they were BIG, like I could fit my hand in my boot big. I've never had…

Love it here!

I've been in this journey for almost a month so I am a sponge absorbing all kinds of information about Zepbound. I tried going on some Facebook groups and oh boy, they are out of…

Switching to zepbound

I’m currently on 2.5mg of wegovy weekly. I have been on it for 6 months. The medication has done nothing for me except intensify sugar and carb cravings. I am switching to…

GOOOOOOOOOOOOOOALLLLLL!

I started Zep on Sept 13, 2025. Originally paying $650 out of pocket (team pens!), I said I wanted to stick with it until March 1 at least. Why? Because tomorrow my family and I…

Confused about how many times one can use Mounjaro Kwikpen

I keep reading the Kwikpen locks after 4 doses. Is this the case? Or it assumes you take the 'proper' amount, say 10mg from a 10mg kwikpen. But if a person takes 5mg from a 10…

Hit my first big goal! Down 30lbs.

Age: 36 Starting weight : November 25’ - 192 Current weight: 162 Goal weight 120-130 Dosage currently 5mg but thinking about going up to 7.5 as I’ve only lost a little…

Weight loss and uncomfortable comments about weight

Trigger warning SA I've battled my weight since I was in my early teens. Around that time I was SA'd and dealt with it all on my own as I felt i couldn't tell anyone. The more…

OCD

For those who use Zepbound or Mounjaro and have OCD: Have you improved? If so, has the improvement continued over the months/years? submitted by /u/Few-Boysenberry-3602 …

Woooooaaaaah we’re half way the-er…

I am now in the 140s. And I’ve finally been cleared to do light rowing after a shoulder surgery last summer. So body composition is about to do a big change up. submitted by …

NSV: 500+ pounds less load exerted on my knees per step!

I’m sure plenty of folks already know, but TIL that for each pound lost, there’s a 4x reduction in the load exerted on the knee per step. That means each of my steps is 500+…

OMG!!We Look so Great Together. My husband and I in our next life ❤️!!

This is my second post of my before and after 80 Lbs. I am just starting to like me I guess. I re-took the,picture both taken on my birthdays, one year apart. Is this going to…

Started last night!

Started my first dose last night! This morning I had no terrible side effects besides a little nausea but it went away fairly quickly. What are some of your experiences the first…

Is tirz really a lot stronger?

Is tirz really a lot more efficient than sema? I saw a friend who started way after me and she’s on tirz and literally lost so much weight. submitted by /u/Glad_Pie8867 …

Mounjaro Made Me a Morning Person? - Week 10 Update As An Average Responder

Some of you might remember my prior posts from a few weeks ago asking about super vs slow responders, as well as my 4 week results post. I thought I'd come back and post more…

Meat aversion

Does anyone else get really bad meat aversion? I feel like it’s getting worse the more I take the shots. Like I’ll crave something with meat & as soon as I start chewing it, I get…

30 días con dutide (resultados + medidas + sensaciones)

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4th 2.5 mg Shot Due Today - Should I move to 5mg the next?

I started Mounjaro three weeks ago and my 4th shot is due today. So far, no major side effects - just mild nausea on injection day and the day after, plus some constipation that’s…

Help with food intake and Mounjaro

Hi all. Due to insurance/office staff reasons beyond my control, I have been off Mounjaro for 3-4 weeks and will likely not be on it for another 2 weeks. I am eating in a 2000…

Didn't lose enough for insurance

My husband's wegovy refill was denied due to not losing enough weight. He had asked his dr to switch medications because it just wasnt working that well. She said no because his…

10 Months in and looking forward to my upcoming Zepiversary

Periodic check in post. I'm proud of these accomplishments but that's not my point today. 10 months ago it hurt to get up out of a chair and I had to twist and contort my body to…

Most weight loss

On 5mg for a month, what’s the most someone can lose? submitted by /u/beginagainagain111 [link] [comments]

Brain and stomach are finally communicating

This is a very new development to my 43 year old self. And its wild. The med is teaching me that the greasy food isnt worth it. Before id ignore the discomfort but now my brain…

What do you miss?

MJ has really put me off coffee. And that was my favourite thing. I’m working my way through different teas and so far the only one that I think “yummy” is raspberry and…

Almost two years in

The picture on the left is me just before I started with tirzepatide. - Feb 2024. My A1C was 5.8. Pic on the right is from October. Some more before and now pics. My A1C is now…

Switching to ozempic, what mg?

Hello. So I’ve been on zepbound since November and have lost 50 pounds. My grandpa can’t take his ozempic anymore due to health reasons and gave me what he had left it’s two boxes…

NSV -- Had to buy new clothes

Many of my pants can't stay on my waist anymore even with a belt. I also tried on some pants I had in my closet from my thinner days, and they're now wearable. So had to get some…

The Progression Jan 2024 to Feb 2026

From 202 to 138 lbs. submitted by /u/Hefty-Status8681 [link] [comments]

Please tell me your experience with alcohol on this Mounjaro!

I’m starting the medication within a couple of weeks and am most excited that it might help with alcohol cravings. I’m fat because I’m an alcoholic; I don’t eat much. I’d love to…

MOUNJARO INJECTION INDIA?

Hey guys, I really wanted to try out the MOUNJARO injection. I’m current in Kerala and if there’s anyone actually tried and has experienced positive results do let me know. I…

I can’t believe it’s been eight months.

I I started Zep on August 7, 2025 after my dr finally convinced me that I was predictive , my blood pressure wasn’t under control even with a high dose of meds . I was scared but…

GLP-1 Drugs Tied to Unexpected Migraine Benefits

(MedPage Today) -- Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department (ED) visits than those on…

Injection question

Recently went up in dosage to 1.7mg. Instructions say to inject 43 units per syringe. My syringes go in 2s. So 40,42,44,46,48,50 etc. I assume I’m just getting as close to 43 as…

Mounjaro over

Als je het zelf niet meer gebruikt kan je het dan ergens kwijt in Nederland? submitted by /u/PutridSafe8291 [link] [comments]

Restarted 5mg after 2+ week break — feeling really off

I’m a 22-year-old female, 5’9”, and I started Mounjaro at 190 lbs. I’ve been on it for about 9.5 weeks now (4 weeks at 2.5 mg, then 5 mg after that). I’m currently 179 lbs, so…

Does your body eventually become immune to meds?

I started with a microdose of .20 mg…..I stayed there for about two months and it worked great. Eventually, I had to increase dosage because I wasn’t feeling the same effects. …

Anyone have LESS or mitigated side effects when increasing to 1mg?

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1mg

Anyone have LESS or mitigated side effects when increasing to 1mg? submitted by /u/FearlessSpirit6467 [link] [comments]

-26 lbs, feeling happier and healthier!

submitted by /u/Bridgelogs [link] [comments]

Community Weekly Goals

As we all work towards our common journey.... our paths may be different, but the end goal is the same. Let's hold each other accountable. What is this week's goal for you? What…

ONEDERLAND and 95% to my goal!! 90lbs J. Thanks to everyone for sharing thier story

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Finally broke through my fluctuations from TOM and other factors, was stuck fluctuating for 2 weeks 7-8-9 and today I got a WHOOSH of 1.2lbs!

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186 lbs to 130lbs since starting late May of 2025. 1st photo is now, second was just over a year ago.

I’ve been at 7.5 mg for the last 5 months. I have 10 more lbs till my goal weight. (I’m only 5’1”). It all seems to happen when I stopped paying attention. I went over a month…

Prolonged ileus-like symptoms after Ozempic? Anyone else experience this?

Hi everyone! I’m looking to see if anyone has experienced something similar. I took my last 0.25mg dose of Ozempic on 2/11. Since mid-February, I’ve had: • Severe abdominal…

SW: 256 CW: 125

I did it. This took longer than I wanted. It wasn’t dramatic. It wasn’t fast. And there were so many moments I thought my body was working against me. When I started in March…

First social encounter and “fat” as a state of mind…

Last night I went to a friends birthday, it was the first time seeing anyone I know since losing weight. My friend noticed and just made the acknowledgment and I felt good. Then…

Day 3, Wegovy 1.5

Down 2.8 lbs. to 206.4! I’m drinking a lot more water after feeling lightheaded yesterday, and it seems to be working. Less bloating and gas today. Starting strength training…

Nausea

How common is nausea on starter doses? I’ve never experienced any nausea whatsoever, have had mild side effects, coldness and urgent hunger being the most uncomfortable side…

Ozempic for binge eating disorder

Hi guys, I have BED and I have done a lot of research and found out that Ozempic or mounjaro helped a lot of people against it. The only problem is that I don’t have obesity, so…

New doc won't prescribe

I'm in Canada - any suggestions? My doctor left my city, and I had a few refills. Now that I'm out, my new doc is refusing to prescribe. Any idea where I can still get ozempic? I…

9 months on Wegovy

​ 48(F) SW-146.5kg (323lb); CW-122KG (269lb) Hashimoto's Thyroiditis (medicated) Depression/Anxiety (medicated) Fibromyalgia ADHD ARFID I'm in the UK and managed to get a…

Finally Starting to See a Difference!

I’ve had a closet full of clothes that I can’t fit into for as long as I can remember. Just decided to try on these jeans again today and they slipped on easily! In November I…

A happy flight

Crossed legs and a healthy seat belt “tail.” 268➡️150 lbs. January 2025-present submitted by /u/No-Effort5109 [link] [comments]

Progress Pics! 233.3>170lbs GW: 135-45

I finally got these jeans back after a month (long story) and WOW! They are actually getting loose?? I can't believe how far I've come! Only 30lbs to go! submitted by …

Still can't believe it after 7 months

First off, never thought I would make a post like this with pics, but after having these results, I needed to share it with someone. First initial pictures are from my 1st shot…

Husband says I am to skinny

My husband made a comment this morning that really caught me off guard, and I’m not sure how to handle it. He was already in a bad mood about other things and going on a rant. In…

1st shot done yesterday

Hey everyone. I just started my journey yesterday when I took my first shot. Here’s a question for those who have been doing this awhile: when will I feel like having something to…

Diet Pepsi

Yes I know it’s horrible for you - but are most still able to drink Diet Pepsi when on ozempic? Thanks submitted by /u/Same_Jackfruit470 [link] [comments]

Looks like we made it! 🎶

It’s been a slow roll for the past couple of months as I got closer and closer to a healthy weight range. Nevertheless, I’ve been hanging in there and sticking with my normal…

Restarting after Surgery

64FT2D, since 11/2023, 10 mg doesage, last A1C 5.1. HW 270, SW 215 CW 165- ish just had a tummy tuck and lipo with muscle repair on 2/23 Per doctor, stopped mounjaro 1week…

OMG, this really works!

I’m pinching myself. 6 months in, 32 pounds gone! Highest weight was 230, lost about 40 pounds years ago, maintaining around 200 for the last couple of years. Started meds Aug…

Thinking of starting Wegovy, how to change suppliers

I’ve been looking at starting Semaglutide. Obviously I want to make this as reasonable as possible money wise. I saw someone on another post saying they change suppliers often to…

Online Dr. that will send my prescription to a local pharmacy?

Hello, I'm pre diabetic and slightly obese. My PCP says I don't quite meet the qualifications for a prescription bc my bloodwork is barely below the trigger where he'd prescribe…

Midsection - 1 year later

Started on sema in February 2025, switched to Zep In September 2025 and currently on 12.5 (the first dose I really felt). Down 70 lbs altogether but the difference to my stomach…

Just started and I’m checking in.

Hello everyone. I (41m, 6’ 1”, 315lbs) was just prescribed Ozempic .25mg this week and took my first dose 2 nights ago. Was prescribed for T2 Diabetes. I’m also on Metformin…

Wegovy & PCOS

Hi All, does any here take Wegovy, Alongside having pcos? If so, i'd like to hear your experiences with it. Challenges, benefits etc. :) submitted by /u/One-Clue3819 …

Skipped a dose

I was take 1.5mg for 3 weeks but began to feel so nauseous for days. I decided to skip a dose to help myself feel better. I’m going to go back to .9mg until it doesn’t work…

In total shock

I’ve had a couple NSV’s lately. First was the picture on the left from 4 years ago. I barely recognize her! My face has changed so much! The second was last night. We were at…

My 1 year Zepversary!

Reposting with edits to photos to blur out my partner 😅 So happy to have made it one year on Zep! I still have a ways to go but this sub has taught me that it's an entire…

Kidney problems

hello everyone. I have been on ozempic for 4 months 0.25 and I have kidney problems. I went to the doctor and taking care of it no worries! However my family told me that maybe…

Anyone else get this weird throat symptom? Pls tell me I’m not being silly

Hi, Posting to see if anyone else has gotten these side effects? Trying to figure out if it is related to semaglutide or not. The issues are: - throat itching - tightness …

When you quit Zepbound

I quit Zepbound cold turkey few weeks ago and wanted to share what happened. Appetite comes back roaring and weight goes up rapidly. I am planning to get back on in few weeks if…

Any advice on maintenance and dose changes

I just hit my dream weight and utterly shocked it worked as well as it did and neeeeever thought I’d be here. I’m nowhere near ready to stop and envision taking forever but…

Cold Turkey, No Maintenance

I’ve reached 6.0 A1C. I’ve lost weight - maybe too much? My doctor took me off ozempic completely. I thought I would go on a maintenance dose or dose less frequently. Should I be…

Ozempic - Effect on irritable bowel syndrome (IBS) or other autoinmune conditions?

Hi, I have been reading very conflicting information regarding Ozempic and its effect in IBS and autoinmune conditions. I would like to know your experiences! To clarify, I am…

The dreaded “bubble”

It finally happened to me. As soon as I inserted the needle I knew something was wrong. I should have switched to a new needle, because it hurt the first time I tried to insert…

Bladder changes?

Strange but has anyone noticed urinary frequency changes with glp? On my injection increase day I feel like I peed every 30 minutes. The day after, I drank 2L of water + a few…

How far into the medication did you start noticing…

How far into the medication did you start noticing your appetite decrease? Side effects? Weight loss? Just trying to understand a general timeline. submitted by …

Food aversions to eggs and all meats

I started semaglutide 3 weeks ago, and for about a week and a half now I am having aversions to eggs and meat (unless it’s highly processed - like chicken nuggets).. I have never…

Prescribed Ozempic

Please tell me you guys aren’t paying $700 for this??? My Kaiser pharmacy shows ready for pick up and my jaw dropped to the ground when I saw that it’s going to cost me $675!! I…

Inconsistent suppression. Time to move up to 2.0mg?

I've been on 1.0mg for 4 months and have only lost 11 lbs. What's most frustrating to me is the inconsistency in restriction. I'll take the medication weekly and I won't feel…

Ozempic 1 mg for 3 months — suddenly need to poop after eating

I’ve been on Ozempic for about 6–7 months and gradually increased my dose. I’ve been on the 1 mg dose for around 3 months now. In the past 2–3 weeks, I’ve noticed that almost…

10lbs down in 2 weeks! I started my journey on Valentine's Day and built a free tool to help us track progress.

Demo of the app Hey everyone, I officially started my GLP-1 journey on Valentine’s Day this year and honestly I’ve never felt better. I’m already 10 pounds down in just two…

Australians - q re Ozempic on PBS for Type 2 diabetes

Hi Aussies, is there anyone here who got prescribed Ozempic on the PBS? I am worried that even though my health is awful, I haven’t “failed” my current meds badly enough to…

What nutrition advice did your doctor actually give you when they prescribed?

Genuinely curious — when you got your prescription, what did your doctor or prescriber tell you about what to eat? I've been going down a rabbit hole on this and keep reading…

6 months || -35 lbs || 192 to 157 || 5'7"

I've been so encouraged to see others' progress here (thank you!!) so I decided to share mine so far. Went from 192 lbs to 157 (87kg to 71kg) in 6 months. I'm 5'7" and in my late…

Please tell me it gets better

I started ozempic on Thursday for my T2 diabetes and have honestly never felt as ill as I have for the last couple of days. I couldn’t keep any food down at all and had the worst…

I'm an RD specializing in GLP-1 therapy. AMA!

Hi everyone! I'm an Registered Dietitian specializing in GLP-1 therapy. I’ve seen a lot of confusion regarding how to eat for the best success on these medications. I'm a strong…

Where is MY end game?

Currently still on .025 per week. Considering increasing that. Because I have "plateaued" at 210. My A1c is below 6 and I take only 15 mg of Lantus and 1000 mg of Metforman. I…

Ozempic

Hey everyone! I searched and searched and finally found a group about Ozempic. Listen, I have type 2 diabetes. My family doctor prescribed Ozempic. I weigh a total of 92 kg. On…

Just had an old picture of me pop up on memories

Looking at the comparison is shocking 300isk pound to 214 today. I still have about 60’pounds to go but just seeing the difference is crazy in a year! submitted by …

Is anyone else a little in love with this community?

I mean it. With a few exceptions, everyone on this subreddit is so kind, generous, supportive, informative and genuine. (Same with r/zepbound) It's one of my favourite cozy…

Progress Pic - 5mg since August

Diagnosed with T2 diabetes in August - strong family history plus PCOS and Gestational Diabetes both pregnancies (passed my postpartum glucose tolerance test though). Upon my T2…

Feel like a new man

5 stone 8 gone for good submitted by /u/3timesme [link] [comments]

Pain Discovery

What do you actually eat on days when you feel nauseous or can’t eat much? I have been reading a lot about GLP-1 meds and I am curious, on those days when your appetite is…

On the fence about Semaglutide? Do it

I've been a long time lurker, especially when I was considering using Semaglutide, and honestly, I woke up, felt great today, and decided to share my story for other lurkers who…

Success story!

Hi everyone. I’m 33F with PCOS and hypermobility, insulin resistance, inflammation, IBS, etc. The whole plethora of other issues that come with these. I started taking Mounjaro in…

Update 72 pounds less in 9 months

Hi everyone! I wanted to give you guys an update. I use wegovy I’m a F36 y/o, 5’5. Mom of two kids. Initial weight: 271 pounds Current weight :199 pounds So I was losing…

AMA: Lost 22kg (48lbs) on Wegovy as a shift worker – 8 months of real data, 4 month break, no gym, and the unexpected effect nobody talks about

I’ve been lurking here for months, reading everyone’s experiences while documenting my own. Today I’m sharing everything. Ask me anything. Who I am 30 years old, 1.88m (6’2”),…

Lilly’s GLP-1 pill tops Novo’s Rybelsus in head-to-head trial

Orforglipron, which could be approved for obesity next quarter, proved superior at cutting blood sugar and body weight — but at the expense of higher side effect rates.

The overlooked nutrition risk of Ozempic and Wegovy

Popular weight-loss drugs like Ozempic and Wegovy can dramatically curb appetite, but experts warn many users are flying blind when it comes to nutrition. New research suggests…

This weight loss option beats Ozempic by 5 times

Bariatric surgery far outperformed GLP-1 weight loss drugs in a new real-world comparison of more than 50,000 patients. Two years after treatment, surgery patients lost about 58…

Her food cravings vanished on Mounjaro then roared back

Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about…

How to keep Ozempic/Wegovy weight loss without the nausea

Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help…

Wegovy in a pill? Massive weight loss results revealed

Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy. The pill also improved cardiovascular risk factors and…

Ozempic and Wegovy protect the heart, even without weight loss

Semaglutide appears to safeguard the heart even when patients lose little weight. In a massive international trial, heart attack and stroke risk dropped by 20% regardless of BMI.…

Ozempic, Wegovy and Mounjaro makes food taste sweeter and saltier, and that may quiet cravings

Some people taking Ozempic, Wegovy, or Mounjaro notice that food suddenly tastes sweeter or saltier, and this subtle shift in flavor perception appears tied to reduced appetite…

The next Ozempic: A 4-in-1 breakthrough for lasting weight loss

Scientists are racing to improve weight loss treatments beyond drugs like Ozempic and Wegovy, which are effective but plagued by nausea, bone loss, and weight regain. Tufts…

Losing weight but gaining weakness? What Ozempic might be doing to your muscles

Ozempic’s weight loss benefits might come at the cost of muscle strength, even if muscle size remains relatively stable. This raises significant concerns for older adults, who are…

Fat melts away, but so does muscle: What Ozempic users need to know

GLP-1 drugs like Ozempic are transforming weight loss, but a new UVA study warns they're not improving a critical measure of health: cardiorespiratory fitness. While these…

Brain food fight: Rutgers maps the hidden switch that turns cravings on and off

Rutgers scientists have uncovered a tug-of-war inside the brain between hunger and satiety, revealing two newly mapped neural circuits that battle over when to eat and when to…

Beyond Ozempic: New weight loss drug rivals surgery

Tufts University scientists are aiming to revolutionize the future of weight loss drugs by engineering a new compound that targets four gut hormones instead of the usual one to…

Newly identified group of nerve cells in the brain regulates bodyweight

Obesity is a global health problem that affects many people. In recent years, very promising anti-obesity drugs have been developed. Despite these successes, there are patients…

REMINDERS

Good Morning! I hope everyone had a great weekend. It’s been a while since we posted any reminders, and I’d like to touch on a couple of issues that have come up recently. With…

Y'all need to read the r/Ozempic rules!

Hey there! Mod here. You all need a rule refresher because the sheer amount of illegal sales, lifestyle and body shaming, T2D vs weight loss and just plan asshole comments are…

Approved provider list

We are compiling a list of providers and health practitioners, if you would like to be featured on the list which will be a sticky post please contact the moderator team. …

Semaglutide subreddit FAQ

This was created based off community suggestions. If you have an IMMEDIATE medical concern, PLEASE talk to your doctor - not random people on the internet. Q1: Does my insurance…